A condemned man that is scheduled to hang the following day uses his last request to ask Sherlock Holmes to prove his innocence of the murder for which he is about to be executed.

While walking along the banks of the River Thames, Watson finds a diamond tooth. The article soon takes on further meaning, however, when Holmes learns that the body of a murder victim was found close to where Watson found the tooth.

When Holmes meets an injured man carrying an unconscious woman, he discovers that the man is an engineer who was hired by another man to fix a large hydraulic press, but upon arriving to tackle the job, things did not go as planned.

Malcolm MacGregan seeks Holmes's assistance in solving the mystery of a ghost who never fails to prevent the sale of an ancestral painting.

A cowgirl from a visiting rodeo exhibition requests Sherlock Holmes' immediate assistance after she discovers a dead man in her bedroom.

Dr. John Watson meets private detective Sherlock Holmes and assists him in solving a case that has otherwise confounded Inspector Lestrade of Scotland Yard.

When a man Mr. O'Casey and a woman split the purchase of a lottery ticket three ways with disappears, O'Casey hires Holmes to find the man. The three had torn the ticket into three pieces, and the deadline to claim the prize is midnight.

After a notorious criminal is killed by a milk-wagon, Lestrade finds a coded message in the man's clothing, and asks Holmes to decipher it. The investigation leads Holmes to assume the dead man's identity and travel all the way to Paris.

While Holmes and Watson are away from London on vacation, someone has taken the opportunity to impersonate Holmes - to a great profit.

After a boy flees his compartment on a train, he suddenly disappears into thin air. Although his governess believes that he has simply run away, Holmes has other suspicions. Holmes' inquiry into the matter leads him to a nearby circus.